Alpha 2-agonists reduce IOP ________%.

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Multiple Choice

Alpha 2-agonists reduce IOP ________%.

Explanation:
Alpha-2 adrenergic agonists lower intraocular pressure primarily by reducing aqueous humor production through stimulation of receptors in the ciliary body. In clinical practice, the typical average IOP reduction with this class is around 20%. So, 20% best represents the common magnitude of effect you’d expect with brimonidine or apraclonidine. Smaller reductions like 10–15% are less characteristic, while 30% is larger than what this drug class usually achieves, though individual responses can vary.

Alpha-2 adrenergic agonists lower intraocular pressure primarily by reducing aqueous humor production through stimulation of receptors in the ciliary body. In clinical practice, the typical average IOP reduction with this class is around 20%. So, 20% best represents the common magnitude of effect you’d expect with brimonidine or apraclonidine. Smaller reductions like 10–15% are less characteristic, while 30% is larger than what this drug class usually achieves, though individual responses can vary.

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