Apraclonidine and brimonidine are what type of receptor agonists?

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Multiple Choice

Apraclonidine and brimonidine are what type of receptor agonists?

Explanation:
Apraclonidine and brimonidine lower intraocular pressure by activating alpha-2 adrenergic receptors in the eye, especially on the ciliary body. Stimulation of these receptors reduces aqueous humor production, which lowers IOP; brimonidine is particularly selective for alpha-2 receptors, helping to minimize other receptor‑type effects. These drugs may also modestly enhance uveoscleral outflow, contributing to the pressure reduction. They’re not alpha-1 adrenergic agonists, which have different vascular effects; nor muscarinic antagonists, which work through a different parasympathetic mechanism; nor beta-adrenergic agonists, which aren’t used to lower IOP.

Apraclonidine and brimonidine lower intraocular pressure by activating alpha-2 adrenergic receptors in the eye, especially on the ciliary body. Stimulation of these receptors reduces aqueous humor production, which lowers IOP; brimonidine is particularly selective for alpha-2 receptors, helping to minimize other receptor‑type effects. These drugs may also modestly enhance uveoscleral outflow, contributing to the pressure reduction. They’re not alpha-1 adrenergic agonists, which have different vascular effects; nor muscarinic antagonists, which work through a different parasympathetic mechanism; nor beta-adrenergic agonists, which aren’t used to lower IOP.

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