Beyond increasing outflow through the trabecular meshwork, netarsudil also lowers what?

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Multiple Choice

Beyond increasing outflow through the trabecular meshwork, netarsudil also lowers what?

Explanation:
Netarsudil lowers episcleral venous pressure in addition to increasing trabecular outflow, and that matters because the conventional drainage pathway carries aqueous humor from the anterior chamber into the episcleral veins. The driving force for outflow is the gradient between intraocular pressure and episcleral venous pressure (IOP minus EVP). When EVP is reduced, this gradient increases, promoting drainage and lowering IOP. The other options don’t reflect netarsudil’s effects: it doesn’t increase aqueous production, isn’t known for reducing choroidal blood flow as a therapeutic aim, and isn’t associated with pupil dilation.

Netarsudil lowers episcleral venous pressure in addition to increasing trabecular outflow, and that matters because the conventional drainage pathway carries aqueous humor from the anterior chamber into the episcleral veins. The driving force for outflow is the gradient between intraocular pressure and episcleral venous pressure (IOP minus EVP). When EVP is reduced, this gradient increases, promoting drainage and lowering IOP. The other options don’t reflect netarsudil’s effects: it doesn’t increase aqueous production, isn’t known for reducing choroidal blood flow as a therapeutic aim, and isn’t associated with pupil dilation.

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