Carbonic anhydrase inhibitors lower IOP by what percentage?

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Multiple Choice

Carbonic anhydrase inhibitors lower IOP by what percentage?

Explanation:
Carbonic anhydrase inhibitors lower intraocular pressure mainly by reducing aqueous humor production in the ciliary processes. By blocking this enzyme, the rate of fluid formation drops, and IOP falls. For topical CA inhibitors such as dorzolamide or brinzolamide, the typical IOP reduction is around 20% on average, with many patients experiencing roughly 15–25% decreases. While other formulations like oral acetazolamide can produce larger drops, the common, exam-focused expectation for topical CAIs is about a 20% reduction.

Carbonic anhydrase inhibitors lower intraocular pressure mainly by reducing aqueous humor production in the ciliary processes. By blocking this enzyme, the rate of fluid formation drops, and IOP falls. For topical CA inhibitors such as dorzolamide or brinzolamide, the typical IOP reduction is around 20% on average, with many patients experiencing roughly 15–25% decreases. While other formulations like oral acetazolamide can produce larger drops, the common, exam-focused expectation for topical CAIs is about a 20% reduction.

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