How much do ROCK inhibitors lower IOP when added to PGAs?

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Multiple Choice

How much do ROCK inhibitors lower IOP when added to PGAs?

Explanation:
Adding a ROCK inhibitor to a prostaglandin analog gives a modest extra drop in IOP. The ROCK inhibitor works by relaxing the trabecular meshwork and can also lower episcleral venous pressure, which together improves outflow. When used with a PGA, the typical additional reduction is about 2 mmHg, though individual response can vary. So the best answer reflects this small but meaningful extra decrease. Values like 1 mmHg are smaller than what most studies show for the combination, while 4 or 6 mmHg would indicate a much larger additive effect than is usually observed in practice.

Adding a ROCK inhibitor to a prostaglandin analog gives a modest extra drop in IOP. The ROCK inhibitor works by relaxing the trabecular meshwork and can also lower episcleral venous pressure, which together improves outflow. When used with a PGA, the typical additional reduction is about 2 mmHg, though individual response can vary. So the best answer reflects this small but meaningful extra decrease. Values like 1 mmHg are smaller than what most studies show for the combination, while 4 or 6 mmHg would indicate a much larger additive effect than is usually observed in practice.

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