If we have an OHTN/suspect, we should reduce IOP ______ from Tmax.

• A. 10-15
• B. 20-25
• C. 25-30
• D. 30-35

Answer: (B)

In ocular hypertension or glaucoma suspects, the goal is to lessen the highest pressure the optic nerve is exposed to. Focus on reducing IOP from the maximum daytime value (Tmax) makes sense because peaks, not just average pressure, drive risk of conversion to glaucoma and potential progression if damage is present. Aiming for about a 20-25% drop from Tmax provides a meaningful reduction of those peaks while staying within a practical, tolerable treatment target. It balances effectiveness with safety and adherence, and it’s a common starting goal; if Tmax is particularly high or other risk factors exist, the target may be adjusted upward, but 20-25% is a solid, evidence-aligned target to begin with. Implement therapy that lowers production or increases outflow, verify with diurnal IOP monitoring, and adjust as needed.