In a moderate glaucoma patient, what percent reduction from Tmax should be targeted?

• A. 10-20%
• B. 30-40%
• C. 50-60%
• D. 70-80%

Answer: (B)

In glaucoma management, you set a target IOP reduction based on how advanced the disease is. For a moderate case, the goal is a roughly 30–40% reduction from the highest IOP observed (Tmax) before treatment. This level often provides meaningful protection against progression without pushing the eye into unsafe pressures or demanding overly aggressive therapy. For example, if Tmax is 28 mmHg, aiming for about 18–20 mmHg corresponds to a 30–40% drop. Not enough reduction (like 10–20%) may leave progression unchecked, while much larger reductions (50–60% or more) are typically reserved for more advanced disease or very high-risk eyes. Individual factors like anatomy, comorbidities, and tolerance to treatment can adjust the target, but 30–40% off Tmax is the standard range for moderate glaucoma.