What drugs are included in Cosopt, Cosopt PF?

• A. Dorzolamide, Timolol
• B. Brimonidine, Timolol
• C. Dorzolamide, Brimonidine
• D. Latanoprost, Timolol

Answer: (A)

Cosopt and Cosopt PF are fixed‑dose eye drops that pair a carbonic anhydrase inhibitor with a beta‑blocker to lower aqueous humor production. The two active ingredients are dorzolamide, which inhibits carbonic anhydrase in the ciliary body, and timolol, a nonselective beta‑blocker. Cosopt PF is simply the preservative‑free version of the same combination, designed for patients sensitive to preservatives. The other drug pairings listed correspond to different glaucoma combinations (for example, brimonidine with timolol is a different product, dorzolamide with brimonidine is another separate combo, and latanoprost with timolol is yet another). Therefore, the correct combination for Cosopt and Cosopt PF is dorzolamide and timolol.