What is the additional mean IOP reduction associated with Rhopressa?

• A. 1 mmHg
• B. 2 mmHg
• C. 3 mmHg
• D. 4 mmHg

Answer: (B)

Rhopressa (netarsudil) works by increasing aqueous humor outflow through the trabecular meshwork and by lowering episcleral venous pressure, giving a modest but real drop in IOP. When added to existing glaucoma therapy, the typical incremental reduction in mean IOP is about a couple of millimeters of mercury. This add-on effect is consistent with its mechanism, providing an extra push on outflow alongside other agents that may work through different pathways. While some patients may see a bit more or a bit less due to individual variability, the average additional fall is in that modest range, which is why this option is considered the best choice for the question.