What should we base the target IOP off of?

• A. A single IOP reading
• B. Multiple untreated IOP measurements
• C. Post-treatment IOP values
• D. Average daytime IOP

Answer: (B)

Base the target IOP on multiple untreated measurements because IOP varies a lot from day to day and across the day, so a single reading isn’t reliable for guiding long-term risk. Taking several measurements before any treatment gives a clearer picture of the patient’s true baseline pressure and its range, including any diurnal peaks. That baseline is what you want to anchor a personalized target to, so you’re aiming to keep pressures in a safe range for this patient’s specific pattern. Using post-treatment values would reflect the effect of therapy, not the patient’s inherent risk, and could lead to an overly optimistic target. An average daytime value might miss nocturnal or early morning peaks and doesn’t capture the full variability, making it a poorer basis for setting a robust target.