Which fixed combination is Cosopt?

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Multiple Choice

Which fixed combination is Cosopt?

Explanation:
The main concept being tested is identifying the fixed-dose combination that makes up Cosopt. Cosopt is the fixed combination of dorzolamide 2% and timolol 0.5%. Dorzolamide lowers intraocular pressure by inhibiting carbonic anhydrase, reducing aqueous humor production, while timolol is a beta-blocker that also reduces production. Together they provide an additive effect in lowering IOP, which is why this exact pairing defines Cosopt. The other listed pairings mix different drugs (for example, brimonidine with timolol, dorzolamide with brimonidine, or latanoprost with timolol), so they are not Cosopt.

The main concept being tested is identifying the fixed-dose combination that makes up Cosopt. Cosopt is the fixed combination of dorzolamide 2% and timolol 0.5%. Dorzolamide lowers intraocular pressure by inhibiting carbonic anhydrase, reducing aqueous humor production, while timolol is a beta-blocker that also reduces production. Together they provide an additive effect in lowering IOP, which is why this exact pairing defines Cosopt. The other listed pairings mix different drugs (for example, brimonidine with timolol, dorzolamide with brimonidine, or latanoprost with timolol), so they are not Cosopt.

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