Which option lists all the main ocular side effects associated with CAIs?

• A. Stinging, transient blurred vision, bitter taste, allergic reactions, corneal edema, FBS
• B. Stinging only
• C. Blurred vision only
• D. Tearing and redness

Answer: (A)

The main idea here is recognizing the range of ocular side effects seen with carbonic anhydrase inhibitors (CAIs) used for glaucoma. After applying the drop, patients commonly notice stinging or burning and sometimes transient blurred vision due to irritation of the ocular surface. A unique sign with CAIs is a bitter taste, caused by drainage through the nasolacrimal system to the tongue. Allergic-type reactions in the eye can occur, including redness and irritation, and some patients report a foreign body sensation. Corneal edema has been reported in some cases, though it’s less common. Tearing and redness are also seen, but the most comprehensive list of main ocular adverse effects includes stinging, transient blurred vision, bitter taste, allergic reactions, corneal edema, and foreign body sensation. The other options omit several of these key effects, making them incomplete.