Which prostaglandin analog shows the most conjunctival hyperemia?

• A. Latanoprost
• B. Travoprost
• C. Tafluprost
• D. Bimatoprost

Answer: (D)

Conjunctival hyperemia is a common side effect of prostaglandin analogs used to lower intraocular pressure. Among these medications, the one most consistently linked to noticeable redness of the conjunctiva is bimatoprost. It tends to have a higher incidence and more pronounced hyperemia than the others, which is why patients often notice cosmetic for this drug. Latanoprost and travoprost can cause hyperemia as well, but usually to a lesser extent, and tafluprost—especially in its preservative-free form—tends to have the lowest rates. Clinically, this difference in side effects guides choice when a patient is particularly bothered by redness or concerned about cosmetic appearance.