Which statement about dosing frequency and effectiveness is correct for prostaglandin analogs?

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Multiple Choice

Which statement about dosing frequency and effectiveness is correct for prostaglandin analogs?

Explanation:
Prostaglandin analogs lower IOP by increasing uveoscleral outflow, and their effect reaches a plateau with a single daily dose. Because of this ceiling, giving the medication more frequently does not provide a meaningful additional reduction in IOP for most patients. In fact, increasing dosing frequency often raises the risk of local side effects such as redness, irritation, and eyelash changes, and can make adherence harder. So the standard approach—once-daily dosing, typically at night—achieves near-maximal effect with better tolerability.

Prostaglandin analogs lower IOP by increasing uveoscleral outflow, and their effect reaches a plateau with a single daily dose. Because of this ceiling, giving the medication more frequently does not provide a meaningful additional reduction in IOP for most patients. In fact, increasing dosing frequency often raises the risk of local side effects such as redness, irritation, and eyelash changes, and can make adherence harder. So the standard approach—once-daily dosing, typically at night—achieves near-maximal effect with better tolerability.

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