Which statement best describes the systemic side effects of prostaglandin analogs?

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Multiple Choice

Which statement best describes the systemic side effects of prostaglandin analogs?

Explanation:
Prostaglandin analogs used for glaucoma act mainly on the eye to increase outflow of aqueous humor, and they are applied as topical drops. Because their systemic absorption is very limited, they rarely cause systemic adverse effects. Tachycardia, renal impairment, and frequent hypotension are not expected with these drugs. The typical adverse effects are local to the eye—conjunctival redness, eyelash growth, iris darkening, and mild periorbital changes—rather than systemic issues. So the statement that there are no common systemic side effects best reflects their safety profile, making that option the correct choice.

Prostaglandin analogs used for glaucoma act mainly on the eye to increase outflow of aqueous humor, and they are applied as topical drops. Because their systemic absorption is very limited, they rarely cause systemic adverse effects. Tachycardia, renal impairment, and frequent hypotension are not expected with these drugs. The typical adverse effects are local to the eye—conjunctival redness, eyelash growth, iris darkening, and mild periorbital changes—rather than systemic issues. So the statement that there are no common systemic side effects best reflects their safety profile, making that option the correct choice.

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