Which term describes the gradual rise in IOP with long-term beta-blocker use that can be reversed by short-term discontinuation?

Boost your readiness for the Primary Open-Angle Glaucoma Test. Utilize flashcards and multiple-choice questions complete with hints and detailed explanations to enhance your understanding.

Multiple Choice

Which term describes the gradual rise in IOP with long-term beta-blocker use that can be reversed by short-term discontinuation?

Explanation:
This describes a gradual waning of the IOP-lowering effect of chronic beta-blocker therapy that can reset with a brief drug holiday. Over months to years, the eye’s response to a beta-blocker can slowly diminish, causing IOP to creep up despite continued treatment. A short discontinuation allows the system to regain sensitivity, effectively reversing the drift when the drug is reintroduced. This differentiates it from tachyphylaxis, which is a rapid loss of response; short-term escape, which occurs early after starting therapy; and rebound effect, which is an overshoot in IOP after abrupt withdrawal.

This describes a gradual waning of the IOP-lowering effect of chronic beta-blocker therapy that can reset with a brief drug holiday. Over months to years, the eye’s response to a beta-blocker can slowly diminish, causing IOP to creep up despite continued treatment. A short discontinuation allows the system to regain sensitivity, effectively reversing the drift when the drug is reintroduced. This differentiates it from tachyphylaxis, which is a rapid loss of response; short-term escape, which occurs early after starting therapy; and rebound effect, which is an overshoot in IOP after abrupt withdrawal.

Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy